UK news The nasal flu spray being developed that could protect against Covid last minute news
PremierLeague-News.Com- New vaccine technique could be adapted to fight other pathogens such as the coronavirus
PremierLeague-News.Com - Breaking Sport Transfer News ! A simple flu spray that could protect people against every strain of that virus could also be used against Covid, a new study has shown. In a recent research paper, the spray is said to give a broad protection against a number of viruses and pathogens - offering hope of a front-line defence against potentially lethal forms of the flu virus. Recurring seasonal epidemics and potential pandemics are among the most severe threats to public health, say the US team. The vaccine contains a protein called HA (recombinant hemagglutinin) that is found on the surface of all types of viruses. HA works by stimulating the body's immune system to build antibodies that attack this protein. Flu is difficult to fight because it can 'evolve' and learn to protect itself against drugs quickly. The new spray could solve the problem, reports HullLive. You can find your nearest vaccination centre in your local area in the widget below: Senior author Dr Baozhong Wang, of Georgia State University, said: "Our research opens a new path for the development of needle-free and logistically simplified intranasal flu vaccines for cross-protection." The nanoparticles are administered through the nose to boost the immune system. Current vaccines don't work against mismatched strains. More effective alternatives are urgently needed. Nasal sprays are a particularly "promising strategy". Respiratory tracts are the portal of virus entry - preventing infection at the key spot. They can also stimulate systemic immune responses throughout the body. Vaccines injected into a muscle don't induce them in mucous. The solution described in Proceedings of the National Academy of Sciences combined HA with a chemical called graphene oxide. Read More Related Articles Stansted Airport rules from May 17: When foreign holiday destinations will be listed under new traffic light system Read More Related Articles Universal Credit, PIP, ESA and other new benefit changes coming in May Dr Wang said: "Conventional flu vaccines predominantly induce antibody responses.
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. "The development of lung resident T cell responses requires vaccination by a respiratory route or influenza virus infection. "Our research opens a new path for the development of needle-free and logistically simplified intranasal flu vaccines for cross-protection." In tests on mice and human cells cultured in the lab, the vaccine produced antibodies.
Dr Chunhong Dong
Lead author Dr Chunhong Dong, a member of the same lab, said: "In our study, we reported for the first time that two-dimensional graphene oxide nanomaterials had a potent adjuvant effect in boosting the immune responses of intranasal hemagglutinin (HA) vaccines." The nanoparticles significantly enhanced immune responses in mucous and throughout the rodents' bodies. The robust reaction also conferred protection against different virus strains. Dr Dong said: "This study gives new insights into developing high performance intranasal vaccine systems with two-dimensional sheet-like nanoparticles.
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"The graphene oxide nanoparticles have extraordinary attributes for drug delivery or vaccine development, such as the ultra-large surface area for high-density antigen loading, and the vaccine showed superior immunoenhancing properties in vitro and in vivo. "The nano-platform could be easily adapted for constructing mucosal vaccines for different respiratory pathogens." Needle-free flu sprays possess superior logistical advantages over a jab, added the researchers. They include easy administration with high acceptance rates and the avoidance of biohazardous waste.
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